Vascular

SSIs are the third most commonly reported type of healthcare-acquired infection and the most costly¹. They place a significant impact on patient welfare² as well as presenting a heavy financial burden for the NHS³.

Leukomed^® Sorbact^® is an innovative post-operative film dressing with a purely physical mode of action, used to prevent surgical site infection (SSI) in closed surgical wounds. Following rigorous assessment by leading clinical and health economic experts during the NICE Medical Technology appraisal process it is proposed that Leukomed Sorbact should be considered as an option for preventing surgical site infection (SSI) in wounds with low to moderate exudate after caesarean section and vascular surgery. It should be used as part of usual measures to help reduce the risk of surgical site infection*.

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Leukomed Sorbact reduces SSI after vascular surgery

In the prospective non-randomised Bua et al. 2017 study there were fewer SSIs with Leukomed Sorbact compared to standard dressings at 5 to 7 days. Overall total incidence within 30 days saw a 47% relative risk reduction in the DACC group.

In addition, evidence suggests that Leukomed Sorbact:

reduces SSI in caesarean section and vascular surgery
may reduce antibiotic use
may reduce readmissions from wound complications

Potential cost savings

Cost savings are anticipated as Leukomed Sorbact is expected to reduce re-admissions and shorten the length of stay in hospital. For more details see the NICE resource impact report*.

Reducing SSI rates can reduce readmissions, antibiotic use, offer cost savings and benefit patient quality of life.⁴

Supported by clinical evidence

The clinical evidence considered by NICE suggests that Leukomed Sorbact can reduce SSI risk in patients post caesarean section by up to 67% versus standard of care.^6,7

For more information on Leukomed Sorbact and the support available, please click here to send an email enquiry.

*^© NICE 2021 Leukomed Sorbact for preventing surgical site infection.
Available from www.nice.org.uk/guidance/mtg55. All rights reserved. Subject to Notice of rights.
NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication.

Medical references

¹ Wounds UK (2020) Best Practice Statement: Post-operative wound care – reducing the risk of surgical site infection. Wounds UK, LondonCcc
² Taylor L, Mills E, George S, Seckam A (2020) Reducing SSI rates for women birthing by caesarean section. J Community Nurs 34(3): 50–3
³ Jenks PJ, Laurent M, McQuarry S, Watkins R. Clinical and economic burden of surgical site infection (SSI) and predicted financial consequences of elimination of SSI from an English hospital. J Hosp Infect 2014; 86(1):24–33. https://doi.org/10.1016/j.jhin.2013.09.012
⁴ NICE Resource impact report: Leukomed Sorbact for preventing surgical site infection (MTG55) (2021). https://www.nice.org.uk/guidance/mtg55/resources/resource-impact-report-pdf-9011234413
⁵ Totty JP, Moss JWE, Barker E, et al. (2020) The impact of surgical site infection on hospitalisation, treatment costs, and health related quality of life after vascular surgery. Int Wound J. 2020;1–8. https://doi.org/10.1111/iwj.13526.
⁶ Bua. N et al. 2017 Dialkylcarbamoyl Chloride (DACC) Dressings in the Prevention of Surgical Site Infections After Non-implant Vascular Surgery: Annals of Vascular Surgery; 44: 387–392 dx.doi.org/10.1016/j.avsg.2017.03.198 2017 Elsevier Inc. All rights reserved. Manuscript received: October 11, 2016; manuscript accepted: March 28, 2017; published online: 5 May 2017
⁷ Totty, J et al. (2019) Int Wound J. 2019;1–8.